Osteoporosis - causes, symptoms, diagnosis, treatment, pathology

Osteoporosis is a condition where bone density decreases due to increased resorption compared to formation, leading to porous bones and a higher risk of fractures. The bone structure includes cortical bone on the outside and trabecular bone on the inside, with bone remodeling involving osteoclasts and osteoblasts. Genetics, nutrition, hormones, and physical activity affect bone mass maintenance. Diagnosis is made with a DEXA scan, and treatment options include bisphosphonate drugs, teriparatide, thiazide diuretics, denosumab, and raloxifene. Senile and postmenopausal osteoporosis are common types, with vertebral compression fractures as a common consequence. Symptoms are often not present until a fracture occurs.

Methodology

• Bone structure overview
• Bone remodeling process
• Factors influencing bone mass
• Diagnosis with DEXA scan
• Treatment options for osteoporosis

Speakers

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