Summary of Mapping the Brain
Despite the large number of neurobiologists, there is still a limited understanding of how the brain works, which is one of the most complex objects in the known universe.
Connectomics is the mapping of all connections between nerve cells in the brain, similar to genomics mapping genes.
Mapping the brain involves biological challenges as well as imaging, computer science, and software development challenges.
The human brain, when examined at a nanometer scale, generates a massive amount of data, making mapping the entire brain a costly and time-consuming process.
The first connectome was done on a worm with 300 neurons, showcasing the complexity and time-consuming nature of mapping neural connections.
Technological advancements have made mapping the brain more feasible, with the fruit fly brain being chosen for its complexity and manageable size.
Google research assistance and advanced technology have been crucial in processing the massive data sets generated from mapping the fly brain.
Techniques such as 3D convolutional networks and flood filling networks have been developed to automate the tracing and visualization of neurons in the brain.
Mapping the fly brain has revealed that structure is closely related to function, providing insights into the brain's operations.
The next target for Connectomics is mapping the whole mouse brain, which is a miniature version of the human brain and may provide insights into how information is stored in brains.
Understanding the brain's functions, memory formation, and mental disorders requires advancements in technology and collaboration.
Notable Quotes
— 00:15 — « I cant imagine anything more exciting than really finally figuring out how this little object that generates everything we experience actually works. »
— 03:52 — « The Logical next Target for connectomics is a whole Mouse brain its a thousand times larger than a fly brain but still a thousand times smaller than a human brain. »
— 04:25 — « Mouse brain looks exactly like human brain, it is in fact a miniature version of a human brain. »
Category
Science and Nature