CAÍDA del PELO: 3 TRATAMIENTOS que SÍ FUNCIONAN (y uno que aún NO)

Summary

The video explains androgenetic hair loss, compares established treatments with the newer medication clascoterone, and emphasizes that hair-loss treatment and transplantation are not alternatives: a transplant moves follicles, while medication may help preserve remaining hair.

How pattern baldness works

• Dihydrotestosterone (DHT), produced from testosterone by the enzyme 5-alpha reductase, can gradually shrink susceptible hair follicles. Over time, hair becomes thinner and shorter.
• The presenter describes two ways to target this process: reduce DHT production with finasteride or block DHT receptors in the follicles with clascoterone.
• Hair at the back of the head is less affected, which is why follicles from that area can be used in transplants.

Treatments discussed

• Finasteride: In large trials cited in the video, finasteride produced 138 more hairs than placebo in a crown-area measurement after two years. The video also discusses possible sexual side effects and a nocebo effect: in one study, reported problems were more common among men who had been warned about them. This does not mean side effects are imaginary; discuss the risks with a clinician.
• Minoxidil: The video says 5% topical lotion is more effective than 2%. Low-dose oral minoxidil is also discussed, but it may affect blood pressure and is not suitable for everyone. People taking blood-pressure medication should consult their doctor; the video notes particular concern with doxazosin or with taking three or more blood-pressure medicines.
• Topical finasteride spray: A study cited in the video reported a gain of 20 hairs compared with seven with placebo, with much lower drug levels in the blood than with the pill. The presenter notes that the study was funded by the company.
• Hair transplant: A transplant relocates follicles; it does not create new ones. Hair around the transplanted area may continue thinning, so the video says reputable surgeons often recommend ongoing medical treatment. It also advises checking who will perform the procedure and being wary of poorly supervised clinics.
• Clascoterone for hair loss: The video says clascoterone is not currently available for this use. The reported “539% more hair” compares gains between groups, not total hair counts; according to the presenter, the company has not published the absolute numbers. The results have not yet appeared in a peer-reviewed journal, the evidence is largely company-associated, and the treatment has only been tested in men. The presenter says an approval application was planned for early 2027. Do not use the acne cream on the scalp or buy unregulated antiandrogens online.

Practical guidance and self-care

• Ask a dermatologist whether the hair loss is typical pattern baldness or could be related to another cause, such as thyroid problems, iron deficiency, or stress.
• Discuss which option—pill, spray, or minoxidil—best fits your health and other medications.
• If considering a transplant, ask what treatment to continue afterward and whether a qualified surgeon or a technician will perform the procedure.
• Give a treatment around six months before judging its effect. Effective treatment generally needs to be continued. Consult a clinician before starting or stopping medication.
• The video notes an association between this type of baldness in people over 50 and metabolic syndrome, and suggests checking waist size, blood pressure, and glucose. It explicitly says this is an association, not proof of cause.
• In a separate discussion of viewer comments, the presenter praises consistent aerobic exercise and recommends sharing blood-pressure readings with a doctor. For osteoporosis, the presenter says strength training is important alongside any prescribed care. They also caution that vitamin K2 can interact with the anticoagulant Sintrom and advise telling a clinician about its use.

Presenters and sources mentioned

• Presenter/channel: The presenter is not named in the subtitles; the video is from Sento Farmacéutico.
• Research and institutions cited: Julian Imperato-McGinley and Cornell University; Mayo Clinic (hair-transplant tourism review); 1998 finasteride trials; a 15-trial meta-analysis; a Florence study on finasteride and reported sexual side effects; Dr. Baño Galván and the Ramón y Cajal Hospital team; and a Spanish laboratory’s finasteride-spray study.
• Other sources mentioned: Company-funded clascoterone trials and statements from the company’s CEO; viewer commenters Hispano 62 and Tugnoli 66.