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Pharma's Next Big Opportunity? Expert Reveals The Winners In Biosimilars, GLP-1 And CDMO | ET Now

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Summary of the video (biosimilars, GLP-1, and CDMO outlook — ET Now)

US FDA approvals: a key but uneven tailwind for Indian pharma

  • US FDA approvals are described as a tailwind, but erratic and hard to predict, particularly for complex generics.
  • Companies may sometimes wait over a year without receiving the expected approvals.
  • Plain vanilla (“simpler”) generic approvals continue more consistently, helping companies defend base revenues against competition.
  • The larger complex approvals the industry is waiting for have not yet materialized, creating a cautious near-term outlook.

Diversification beyond plateauing domestic growth

  • With domestic growth almost plateauing, pharma companies are seeking new growth engines.
  • The analyst highlights three major areas:
    1. Nutraceuticals / consumer health
    2. Biosimilars
    3. Other innovation-led avenues such as specialty products and services
  • These businesses are expected to require a gestation period before materially contributing to profits, though companies are already investing and ramping up aggressiveness.

Biosimilars: who’s positioned to win

  • Biocon is positioned as an early mover and expected to have a strong next 2 years.
  • “Next ones to watch” for pipeline strength:
    • Dr. Reddy’s
    • Lupin
  • The analyst suggests biosimilars could scale substantially over a 4–5 year horizon, with potential biosimilar top-line contribution of roughly $0.5B to $1B (assuming successful execution).

Emerging profit pools: innovation, CDMO, and specialty

  • Innovation is expected to be less immediate in profitability; it requires investment before returns show up in earnings.
  • Examples of innovation progress mentioned:
    • Sun Pharma: built an innovation platform and created a large business
    • Wockhardt: targeting a larger profit pool from an antibiotic molecule, aiming for commercialization in the US and other markets
    • Zydus: on an innovation journey, planning to launch its first NCE in the US around FY25 year-end / early next year
  • CDMO is framed as another potential profit pool area, with preference for larger, better-positioned firms:
    • Divi’s
    • Laurus
    • Neuland Laboratories (named as an emerging candidate)
    • Piramal Pharma (also mentioned), though outcomes depend on how outsourcing demand shifts from China to India
  • Overall view: more clarity is needed on how much China-origin work transitions to India.

GLP-1 in India: slow start but long-term growth expected

  • Current concerns include:
    • many players (around 15)
    • early oversupply, making growth feel sluggish at the start
  • Despite this, the analyst expects GLP-1 to become very large in India, driven over time by improved patient and physician experience.
  • He expects positive growth each month from the current base as adoption improves.
  • Market share concentration expectation:
    • Top 5–6 players capturing approximately 80–90% of the market.

Domestic formulations: undervaluation angle

  • The discussion turns to whether Indian pharma’s domestic business is undervalued by the market, given strong domestic consumption trends.
  • Analyst’s pick for domestic outperformance and valuation attractiveness:
    • Sun Pharma — described as the fastest-growing among leading domestic players, continuing to outperform peers despite already having a large base, and viewed as attractive from a valuation perspective.

Presenters / contributors

  • Vishal Manchanda — Senior VP, Institutional Research (analyst)
  • ET Now / Host — interviewer (name not specified in the subtitles)

Original video